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  1. Atorvastatin Calcium CAS NO.134523-03-8

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    • Delivery term:

      The date of payment from buyers deliver within days

    • seat:

      Zhejiang

    • Validity to:

      Long-term effective

    • Last update:

      2019-11-01 04:43

    • Browse the number:

      75

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    Company Profile
    ?Hangzhou Jeci Biochem Technology Co .,Ltd.
    Contactaixin:

    jiexi(Mr.)  

    Email:

    telephone:

    phone:

    Arrea:

    Zhejiang

    Address:

    New Town Times Square 4-801, Jianggan District, Hangzhou, Zhejiang, China

    Website:

    http://www.jecibiochem.com/ http://jiexi.szlyqd.com/

    Product details


    Atorvastatin calcium Basic information
















    Product Name:




    Atorvastatin calcium




    Synonyms:




    Atorvastatin Calcium Anhydrous;Calcium of atorvastatin;Atorvastatin ;Atorvastatin aMorphous;atorvastatine calciuM salt;(βR,δR)-2-(4-Fluorophenyl)-β,δ-dihydroxy-5-(1-Methylethyl)-3-phenyl-4-[(phenylaMino)carbonyl]-1H-pyrrole-1-heptanoic Acid CalciuM Salt;Atorvastatin HeMicalciuM;Sortis




    CAS:




    134523-03-8




    MF:




    C66H68CaF2N4O10




    MW:




    1155.36




    EINECS:




    200-659-6






    Atorvastatin calcium Chemical Properties












    Melting point




    176-178°C




    storage temp.




    Store at +4°C




    solubility




    DMSO: ≥10mg/mL




    form




    white powder






    Atorvastatin calcium Usage And Synthesis










    Mode of action




    Atorvastatin takes effect through selectively and competitively inhibiting the hepatic enzyme HMG-CoA reductase, which is responsible for converting HMG-CoA to mevalonate in the cholesterol biosynthesis pathway. This results in a subsequent decrease in hepatic cholesterol levels. Decreased hepatic cholesterol levels stimulates upregulation of hepatic LDL-C receptors which increases hepatic uptake of LDL-C and reduces serum LDL-C concentrations.




    Chemical Properties




    White Crystalline Powder




    Uses




    The primary uses of atorvastatin is for the treatment of dyslipidemia and the prevention of cardiovascular disease.







    Atorvastatin calcium Specification

































    Character




    A white or almost white?crystalline powder




    Identification




    A: IR.

    B: CALCIUM




    water




    3.5~5.5




    Ca %




    3.0~3.6




    Particle size




    D90≤10 μm




    Heavy Metals(ppm)




    ≤20




    Impurity

    (HPLC)




    Impurity E




    ≤0.3%




    Impurity A




    ≤0.3%




    Impurity?B




    ≤0.3%




    Impurity C




    ≤0.3%




    Impurity D




    ≤0.1%




    Other individual unknown Impurity %




    ≤0.1%




    Total impurity




    ≤1.0%




    Assay %




    98.0-102.0


    http://www.jecibiochem.com/

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